[天上掉馅饼] Lihninger's Principles of Biochemistry (4th edition) 下载
[font=palatino linotype]4Ozv9g,M K B注：如果需要 Harper's Illustrated Biochemistry (26th edition)，请点击下面的链接[8] @L"M A/{Im%q$P
[url]http://bbs.taisha.org/viewthread.php?tid=474066&page=1&extra=page%3D2#pid4723630[/url]
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前段时间，我写了个《Amazon购书指导》。在那个帖子的一开始，我就说——能不买就不买7Ek-\~4T,d-Li
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这两天我偶然找到了 [b][u]Lihninger's Principles of Biochemistry (4th edition)[/u][/b]的原版电子书，简称POB4，PDF格式。这是考GRE Biochem Sub最重要的书！以前太傻的FTP上还有这本书配套的CD-ROM软件的下载，两年前我还下载了，不过那个软件很老了。现在POB出到第四版了。这个PDF的电子版正是第四版！p2Pj!L"I"n N*`.t
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电子书非常的精美，也不是很大，30M左右。为了给大家个直观感受，我把第一页从PDF文件作成JPG图片（见图片2）
下面是amazon上这本书的介绍：
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Product Details
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List Price: 137.95 USD L+jz E1p6~
Hardcover: 1100 pages
Publisher: W. H. Freeman; 4th edition (April 23, 2004)
Language: English
ISBN: 0716743396Pg'Q_fY$U
Product Dimensions: 11.2 x 8.8 x 1.8 inches `/Y4a"pE$O a \
Shipping Weight: 6.0 pounds. [/font]
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[[i] Last edited by starcornell on 2005-8-21 at 16:34 [/i]];I(NSc W.N
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[[i] 本帖最后由 starcornell 于 2005-10-19 23:00 编辑 [/i]] [font=palatino linotype][size=4]这本书我分卷压缩成RAR文件，共23个。用FlashGet等软件将所有23个RAR文件下载到同一文件夹下，然后解压缩第一个就OK了[/size][/font] K kS O aY-|
[[i] Last edited by starcornell on 2005-8-21 at 23:20 [/i]] [font=palatino linotype]下面是amazon上一些读者的对这本书的评价：
[b]This book is amazing, February 25, 2005[/b]|5u j z^,E
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Before I say anything about this book, I offer for your consideration the fact that I am not a student of biochemistry; I am a physics graduate student. My desire to learn about biochemistry had nothing to do with receiving any sort of degree. Then consider the fact that this is the only Amazon.com review I have ever written. These facts alone should tell you that I must have found this book pretty remarkable.
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This text was required for all three of the biochemistry classes I took as an undergraduate student, and it never let me down. It contains a positively HUGE amount of information, which Nelson and Cox have somehow managed to digest and present for the layperson in a way that is both engaging and understandable. The writing style is superb, and the visual aids are numerous and of exceptionally high quality.
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How many times while cramming for the next day's test at 3:00 am have you caught yourself reading material that isn't even covered on the exam, just because it's interesting? It happened to me. And while I will admit to having some pretty nerdy tendencies some times, I don't think I'm quite that abnormal.
Don't listen to the reviewers who say they wish this book went into more depth on some issues, because they should know better. I can assure you that there is no lack of depth here. This is an introductory text. You read it if you want an introduction. If the nitty-gritty were found in introductory texts, there would be no need for advanced texts, now would there?
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Coming from a great lover of textbooks, I'll put it to you plainly and simply: Among my top 5 favorite textbooks, this is the only one that isn't about physics. If you are looking for an introductory biochemistry texbook, then I don't believe you can go wrong with this one.[/font]
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[[i] Last edited by starcornell on 2005-8-17 at 00:15 [/i]] [font=palatino linotype]Great Book for Layperson, November 22, 2004
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I'm not a scientist or a student, just someone who was interested in biochemistry as I've been reading a lot about astrobiology and felt I needed a better background in this area. I found this book to be really quite wonderful - beautiful in fact! - with terrific diagrams (my favorite being the e. coli DNA which goes all around the text of the page) - and very well written. It has some incredible diagrams of the proteins involved in biochemistry. Also it has some interesting "asides" covering scientific discoveries or items of medical interest. The discussions of hemoglobin and vitamin B12 were particularly memorable.
Anyway, I can't stop talking about this book to people. I think biochemistry should be required in college for all students, it really makes you appreciate life in a different way than you did before.[/font] [font=palatino linotype]A great book, April 14, 2005&|5T0YCL
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Is there something about biochemistry, which one does not get in the other science (and engineering) fields? My first encounter with Lehninger was as an undergraduate student at Ahmadu Bello University in Nigeria. Though I was majoring in Chemical Engineering, I followed four voluntary courses from the Biochemistry department. Lehninger (2nd edition) was a sine qua non text especially for its thorough, albeit introductory treatment of amino acids, peptides and proteins; carbohydrates; fatty acids and lipids; as well as nucleic acids. I also used it extensively for a course on Bioenergetics.
Years later, I am a graduate student in Chemical Engineering. Yet I chose to order this book to brush up and improve my knowledge of biochemistry. How often do you come in contact with terms such as genomics, proteomics, gene expression and recombinant DNA, wishing you fully knew what they meant? Well, that in part was what drove me to buy this book, coupled also with my desire to become involved in research that cuts across the life sciences and engineering sometime in the future. {n-B }2^&t L ?
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This is a great book. It is very much an introductory text and provides a wealth of information on further texts where one can get hold of advanced information. The authors have done a wonderful job by writing an up-to-date text in which inspires one to learn and look for ways of applying what has been learned. I am not a scientist but an engineer and my field is one that relies on scientific breakthroughs to manufacture products, which make life more comfortable.
The frequent references to medical applications in the text are so beautiful. [/font] [font=palatino linotype]Superb, up to date, clear, comprehensive, February 23, 20057|J|K J$t
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There basically are two top contenders for the #1 position for a biochemistry textbook: Lehninger vs Voet. At first sight, the 1650+ pages Voet text for 'chemistry' oriented students seems like it is too much for the competition. So, how can Lehninger do better in 1100 pages? There are several factors at play, and the 4th edition of Lehninger simply dominates Voet and the rest of the biochem texts out there as follows. The Lehnninger text has a long history, but given that biochemical knowledge doubles every 5 years or so, it matters what a text offers now, not in the past. The writing style is simple, direct, engaging, not too easy but neither too esoteric. The principles (as the title suggests) and the unity in diversity are emphasized, so that the student understands biochemical principles not merely facts, acronyms, pathways. The graphics are very professional. They are comparable to any review article in hot journals such as Nature, Science, Cell, etc. The rendering of protein surfaces, and the different angles through which a structure is seen is outstanding (a good example is the section on the ribosome). The structures have been rendered from the PDB (protein data bank) coordinates. Most are rendered in the ribbon representation, but in many cases the surface is rendered in grey, depending on the level of detail. Contrast this with the 3rd edition of Voet: the authors have not bothered to re-render their graphics, most are identical to the 1995 edition, a time when people only cared if you could generate a structure. Voet's graphics are not done uniformly; the backgrounds can be white, grey, black, some structures are taken directly from the original literature and vary widely in the format and rendering. It is not enough that Voet updated the text on biochemical developments from 1995-2004. The Lehninger pages on the most important protein folds, for example, are very helpful in giving the student a feel for the fold, the domain composition, the size, and names of model proteins one is expected to encounter over and again in the research literature. But pretty pictures are not the only thing that sets Lehninger apart from the rest. The material is distilled such that almost the same ammount of information is contained in this text, even though Voet is 50% bigger. There can be no such text as "Advanced Biochemistry" for grad students etc. -- if one is looking for that sort of thing, then one should purchase a life sciences encyclopedia. For undergraduates, any text is bound to be a bit overwhelming, but Lehninger is clear enough that the above average student should assimilate the material preparing for an exam without too much confusion or difficulty. I also like the typesetting in Lehninger much better than Voet, which again, uses the same boring format as the 2nd 1995 edition. The quality of paper is good in both texts. Lehninger's text feels like the space is utilized well, whereas Voet's space is a bit overcrowded, though strangely, some of the Voet structures are too large, and take up too much space. Lehninger encompases all the new developments up to 2004: RNAi, genomes, new facts on controversial enzyme mechanisms etc. Speaking of enzyme mechanism, both texts do a good job in deriving the Michaelis-Menten equation step by step rather than simply saying something like "through trivial algebra eqn 34 transforms into 45". The literature reference section of Lehninger is one of the best parts of the text: the references are a mixture of classic, outstanding work, and recent review materials, which should guide the more curious student to navigate the overwhelming ammount of information in modern biochemistry and molecular biology. I loved the numerous photos of key players in biochemistry. For example, Francis Crick is shown as a young man when the text refers to the model for DNA, and as a middle aged man in another chapter. The historical emphasis is well placed. The "working in biochemistry" boxes are similarly relevant and well placed. I only wish the current authors had added a brief sketch of Albert Lehninger. In fact, they do not mention the history of the text, which is a little strange. The text contains brief solutions to all the end-of-chapter problems so the solutions manual (unfortunately titled "The Absolute, Ultimate Guide...") is not really neccessary for the good student. I think the criticism that Voet is 'tougher' and has more 'chemistry' in it is not entirely fair. Any researcher cannot expect to find his/her answers for a particular mechanism in any textbook -- that's the whole point of research. The principles on the other hand, can be sufficiently explained with a selection of enzymes and their mechanism, which Lehninger delivers. The metabolism middle part of the book is a bit too large, but it is difficult to avoid this, as when it boils down to it, molecular biophysics and biology have to account for the behavior of a particular system. Grad students these days tend to ignore metabolism, but as they mature, they start to see its point (and the memory slowly starts to assimilate all these enzymes, substrates, products, inhibitors, conditions, pathways...). Voet, of course, also covers metabolism in a comprehensive way. In conclusion, contrary to what Voet reviewers said to "supplement Lehninger with Voet", I am suggesting students get a copy of Lehninger, either from the library or by purchasing their own copy, to supplement any biochemistry text with Lehninger. There is no other text out there that comes close to Lehninger. Which leads to the natural question, "why are there 10-20 biochem books currently in print?". Well, I certainly hope Lehninger will drive out of print most of them:-). Thank you professors Nelson and Cox for the hard and thoughtful work that went into this fourth edition.[/font]
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[[i] Last edited by starcornell on 2005-8-21 at 16:54 [/i]] [font=palatino linotype]A Strong Text, October 27, 2004
This is the only biochem book that I've had, but I'm impressed with it. It explains the concepts to a lot of detail. My professor even uses the reaction mechanisms on his powerpoint slide. The book also comes with a very useful study guide, that makes learning biochem fun, with crossword puzzles and such. [/font] [font=palatino linotype]It continues being the best one., June 27, 2004
The fourth edition of Lehninger Principles of Biochemistry is the best book is the subjet. Like in the third edition the treatment of the topics is very goog. The first chapthers of the past edition were simplified in one single chapter. Also new is an innovative graphical style for depicting enzyme reaction mechanisms. Introduces the human genome. Biochemical insights derived from the human genome are integrated throughout the text.s G j D8D$R |)d
Tracking the emergence of genomics and proteomics, this chapter establishes DNA technology as a core topic and a path to understanding metabolism, signaling, and other topics covered in the middle chapters of this edition. Includes up-to-date coverage of microarrays, protein chips, comparative genomics, and techniques in cloning and analysis.[/font] [size=4][font=palatino linotype]Part 8 [/font] [/size] [size=4][font=palatino linotype]Part 9[/font] [/size] [size=4][font=palatino linotype]Part 10[/font] [/size] [size=4][font=palatino linotype]Part 11[/font] [/size] [size=4][font=palatino linotype]Part 12[/font] [/size] [size=4][font=palatino linotype]Part 13[/font] [/size] [size=4][font=palatino linotype]Part 14[/font][/size] [size=4][font=palatino linotype]Part 15[/font] [/size] [size=4][font=palatino linotype]Part 17[/font] [/size] [size=4][font=palatino linotype]Part 16[/font] [/size] [size=4][font=palatino linotype]Part 18[/font] [/size] [size=4][font=palatino linotype]Part 19[/font] [/size]9a(q)j7L C F
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[[i] Last edited by starcornell on 2005-8-21 at 19:39 [/i]] [size=4][font=palatino linotype]Part 20[/font] [/size]IN2O$L H |-sq
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[[i] Last edited by starcornell on 2005-8-21 at 19:45 [/i]] [size=4][font=palatino linotype]Part 21[/font] [/size]
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[[i] Last edited by starcornell on 2005-8-21 at 19:41 [/i]] [size=4][font=palatino linotype]Part 22[/font] [/size] |-By3_wH
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[[i] Last edited by starcornell on 2005-8-21 at 19:51 [/i]] [size=4][font=palatino linotype]Part 23R'i:` Y[:k;? Q2W
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[[i] Last edited by starcornell on 2005-8-21 at 19:54 [/i]] 抢沙发！厚厚！！！::81::81
谢谢星版主，不过，why不发到sub版去？::p3 啊？！！！！！!ez/Q7oC0Y9O%d
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晕了！！刚刚还在入门区，怎么才发个贴子，就成了sub区？？？？？？？3qUB _*A
::ts::ts::ts 早点发来啊,我在看到了amazon的帖子后就买了这本书了,现在书已经在我书架上了. 领导大人，你终于发完了，沙发也不给我！！！！！！！ [quote]Originally posted by [i]meangirl[/i] at 8/22/2005 02:24 AM
早点发来啊,我在看到了amazon的帖子后就买了这本书了,现在书已经在我书架上了. [/quote]
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我也是前不久找到了
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我还有Harper's Illustrated Biochemistry (26th)。这个你要是需要，我也可以email给你，那个文件不大，10+M的吧。也是PDF，作的很好~'`:S'C Xy
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[[i] Last edited by starcornell on 2005-8-22 at 11:33 [/i]] 贴出来呗 Harper一般是学医的才用~通常考USMLE（United States Medical Licensing Exam）用这个
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要传吗？ 先传上来看看？#rPM&U#d `Q
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[[i] Last edited by 12345beckham on 2005-8-22 at 12:30 [/i]] 下了一下,有的下下来是php,不是rar.居然又出现了以前的问题. 我全下了一遍
没有问题
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都是RAR文件4u HR4pJW8S
用FlashGet Thanks a lot.::z1 谢谢版主。K O'_luK \0k#QM1n
后面的harper对我来说也很important。要考USMLE>.<，能传上来吗？6F2V4gL#zz8K Is3]
再次感谢您的hardwork:D! [quote]Originally posted by [i]soj[/i] at 2005-8-25 18:14
谢谢版主。
后面的harper对我来说也很important。要考USMLE>.<，能传上来吗？
再次感谢您的hardwork:D! [/quote]\ Rg F)jO
[b][size=3][color=Red]您为什么不先把本版的精华先看一下呢？？？？？[/color][/size][/b]
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[url]http://bbs.taisha.org/viewthread.php?tid=474066&extra=page%3D2[/url]
[[i] Last edited by 宋安恬 on 2005-8-25 at 18:43 [/i]] 是不是上sub逛逛md7`8\[1pSr
总能捞到好东西 ::83好东西 实在是非常非常地感谢！！！好东西啊！！！